Correcting for bias in estimation of quantitative trait loci effects

Estimates of quantitative trait loci (QTL) effects derived from complete genome scans are biased, if no assumptions are made about the distribution of QTL effects. Bias should be reduced if estimates are derived by maximum likelihood, with the QTL effects sampled from a known distribution. The param...

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Detalles Bibliográficos
Autores principales: Weller, Joel Ira, Shlezinger, Meital, Ron, Micha
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697222/
https://www.ncbi.nlm.nih.gov/pubmed/16093012
http://dx.doi.org/10.1186/1297-9686-37-6-501

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