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Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics
We considered the analysis of a study for Dorper, Red Maasai and crossbred lambs born over a period of 6 years at the Diani Estate, Kenya. The study was designed to compare survival and performance traits of genotypes with differing susceptibilities to helminthiasis. The available data include infor...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697229/ https://www.ncbi.nlm.nih.gov/pubmed/16194523 http://dx.doi.org/10.1186/1297-9686-37-3-175 |
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author | Nguti, Rosemary Burzykowski, Tomasz Rowlands, John Renard, Didier Janssen, Paul |
author_facet | Nguti, Rosemary Burzykowski, Tomasz Rowlands, John Renard, Didier Janssen, Paul |
author_sort | Nguti, Rosemary |
collection | PubMed |
description | We considered the analysis of a study for Dorper, Red Maasai and crossbred lambs born over a period of 6 years at the Diani Estate, Kenya. The study was designed to compare survival and performance traits of genotypes with differing susceptibilities to helminthiasis. The available data include information on time to death and repeated measurements of body weight, packed cell volume (PCV) and faecal egg count (FEC) of the animals. In the paper, we consider joint modelling of the survival time and the repeated measurements. Such an approach allows to account for the possible association between the survival and repeated measurement processes. The advantages and limitations of the joint modelling are discussed and illustrated using the Diani Estate study data. |
format | Text |
id | pubmed-2697229 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26972292009-06-16 Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics Nguti, Rosemary Burzykowski, Tomasz Rowlands, John Renard, Didier Janssen, Paul Genet Sel Evol Methodology We considered the analysis of a study for Dorper, Red Maasai and crossbred lambs born over a period of 6 years at the Diani Estate, Kenya. The study was designed to compare survival and performance traits of genotypes with differing susceptibilities to helminthiasis. The available data include information on time to death and repeated measurements of body weight, packed cell volume (PCV) and faecal egg count (FEC) of the animals. In the paper, we consider joint modelling of the survival time and the repeated measurements. Such an approach allows to account for the possible association between the survival and repeated measurement processes. The advantages and limitations of the joint modelling are discussed and illustrated using the Diani Estate study data. BioMed Central 2005-03-15 /pmc/articles/PMC2697229/ /pubmed/16194523 http://dx.doi.org/10.1186/1297-9686-37-3-175 Text en Copyright © 2005 INRA, EDP Sciences |
spellingShingle | Methodology Nguti, Rosemary Burzykowski, Tomasz Rowlands, John Renard, Didier Janssen, Paul Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics |
title | Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics |
title_full | Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics |
title_fullStr | Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics |
title_full_unstemmed | Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics |
title_short | Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics |
title_sort | joint modelling of repeated measurements and event time: application to performance traits and survival of lambs bred in sub-humid tropics |
topic | Methodology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697229/ https://www.ncbi.nlm.nih.gov/pubmed/16194523 http://dx.doi.org/10.1186/1297-9686-37-3-175 |
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