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Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics

We considered the analysis of a study for Dorper, Red Maasai and crossbred lambs born over a period of 6 years at the Diani Estate, Kenya. The study was designed to compare survival and performance traits of genotypes with differing susceptibilities to helminthiasis. The available data include infor...

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Detalles Bibliográficos
Autores principales: Nguti, Rosemary, Burzykowski, Tomasz, Rowlands, John, Renard, Didier, Janssen, Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697229/
https://www.ncbi.nlm.nih.gov/pubmed/16194523
http://dx.doi.org/10.1186/1297-9686-37-3-175
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author Nguti, Rosemary
Burzykowski, Tomasz
Rowlands, John
Renard, Didier
Janssen, Paul
author_facet Nguti, Rosemary
Burzykowski, Tomasz
Rowlands, John
Renard, Didier
Janssen, Paul
author_sort Nguti, Rosemary
collection PubMed
description We considered the analysis of a study for Dorper, Red Maasai and crossbred lambs born over a period of 6 years at the Diani Estate, Kenya. The study was designed to compare survival and performance traits of genotypes with differing susceptibilities to helminthiasis. The available data include information on time to death and repeated measurements of body weight, packed cell volume (PCV) and faecal egg count (FEC) of the animals. In the paper, we consider joint modelling of the survival time and the repeated measurements. Such an approach allows to account for the possible association between the survival and repeated measurement processes. The advantages and limitations of the joint modelling are discussed and illustrated using the Diani Estate study data.
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spelling pubmed-26972292009-06-16 Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics Nguti, Rosemary Burzykowski, Tomasz Rowlands, John Renard, Didier Janssen, Paul Genet Sel Evol Methodology We considered the analysis of a study for Dorper, Red Maasai and crossbred lambs born over a period of 6 years at the Diani Estate, Kenya. The study was designed to compare survival and performance traits of genotypes with differing susceptibilities to helminthiasis. The available data include information on time to death and repeated measurements of body weight, packed cell volume (PCV) and faecal egg count (FEC) of the animals. In the paper, we consider joint modelling of the survival time and the repeated measurements. Such an approach allows to account for the possible association between the survival and repeated measurement processes. The advantages and limitations of the joint modelling are discussed and illustrated using the Diani Estate study data. BioMed Central 2005-03-15 /pmc/articles/PMC2697229/ /pubmed/16194523 http://dx.doi.org/10.1186/1297-9686-37-3-175 Text en Copyright © 2005 INRA, EDP Sciences
spellingShingle Methodology
Nguti, Rosemary
Burzykowski, Tomasz
Rowlands, John
Renard, Didier
Janssen, Paul
Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics
title Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics
title_full Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics
title_fullStr Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics
title_full_unstemmed Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics
title_short Joint modelling of repeated measurements and event time: Application to performance traits and survival of lambs bred in sub-humid tropics
title_sort joint modelling of repeated measurements and event time: application to performance traits and survival of lambs bred in sub-humid tropics
topic Methodology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697229/
https://www.ncbi.nlm.nih.gov/pubmed/16194523
http://dx.doi.org/10.1186/1297-9686-37-3-175
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