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A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence
We present a gene-based RH map of the chicken microchromosome GGA14, known to have synteny conservations with human chromosomal regions HSA16p13.3 and HSA17p11.2. Microsatellite markers from the genetic map were used to check the validity of the RH map and additional markers were developed from chic...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697232/ https://www.ncbi.nlm.nih.gov/pubmed/16194526 http://dx.doi.org/10.1186/1297-9686-37-3-229 |
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author | Morisson, Mireille Leroux, Sophie Jiguet-Jiglaire, Carine Assaf, Sirine Pitel, Frédérique Lagarrigue, Sandrine Bardes, Suzanne Feve, Katia Faraut, Thomas Milan, Denis Vignal, Alain |
author_facet | Morisson, Mireille Leroux, Sophie Jiguet-Jiglaire, Carine Assaf, Sirine Pitel, Frédérique Lagarrigue, Sandrine Bardes, Suzanne Feve, Katia Faraut, Thomas Milan, Denis Vignal, Alain |
author_sort | Morisson, Mireille |
collection | PubMed |
description | We present a gene-based RH map of the chicken microchromosome GGA14, known to have synteny conservations with human chromosomal regions HSA16p13.3 and HSA17p11.2. Microsatellite markers from the genetic map were used to check the validity of the RH map and additional markers were developed from chicken EST data to yield comparative mapping data. A high rate of intra-chromosomal rearrangements was detected by comparison to the assembled human sequence. Finally, the alignment of the RH map to the assembled chicken sequence showed a small number of discordances, most of which involved the same region of the chromosome spanning between 40.5 and 75.9 cR(6000 )on the RH map. |
format | Text |
id | pubmed-2697232 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26972322009-06-16 A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence Morisson, Mireille Leroux, Sophie Jiguet-Jiglaire, Carine Assaf, Sirine Pitel, Frédérique Lagarrigue, Sandrine Bardes, Suzanne Feve, Katia Faraut, Thomas Milan, Denis Vignal, Alain Genet Sel Evol Research We present a gene-based RH map of the chicken microchromosome GGA14, known to have synteny conservations with human chromosomal regions HSA16p13.3 and HSA17p11.2. Microsatellite markers from the genetic map were used to check the validity of the RH map and additional markers were developed from chicken EST data to yield comparative mapping data. A high rate of intra-chromosomal rearrangements was detected by comparison to the assembled human sequence. Finally, the alignment of the RH map to the assembled chicken sequence showed a small number of discordances, most of which involved the same region of the chromosome spanning between 40.5 and 75.9 cR(6000 )on the RH map. BioMed Central 2005-03-15 /pmc/articles/PMC2697232/ /pubmed/16194526 http://dx.doi.org/10.1186/1297-9686-37-3-229 Text en Copyright © 2005 INRA, EDP Sciences |
spellingShingle | Research Morisson, Mireille Leroux, Sophie Jiguet-Jiglaire, Carine Assaf, Sirine Pitel, Frédérique Lagarrigue, Sandrine Bardes, Suzanne Feve, Katia Faraut, Thomas Milan, Denis Vignal, Alain A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence |
title | A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence |
title_full | A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence |
title_fullStr | A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence |
title_full_unstemmed | A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence |
title_short | A gene-based radiation hybrid map of chicken microchromosome 14: Comparison to human and alignment to the assembled chicken sequence |
title_sort | gene-based radiation hybrid map of chicken microchromosome 14: comparison to human and alignment to the assembled chicken sequence |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697232/ https://www.ncbi.nlm.nih.gov/pubmed/16194526 http://dx.doi.org/10.1186/1297-9686-37-3-229 |
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