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Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient

With the expanding use of immunosuppressive therapies and broad-spectrum antibiotics, Candida species has become an increasingly important cause of infections, particularly in the presence of anti-tumor necrosis factor-α therapy. We report the case of a 17-year-old female with ulcerative colitis who...

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Detalles Bibliográficos
Autores principales: Tee, James B., Reznik, Vivian, Krous, Henry F.
Formato: Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697366/
https://www.ncbi.nlm.nih.gov/pubmed/19296134
http://dx.doi.org/10.1007/s00467-009-1160-7
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author Tee, James B.
Reznik, Vivian
Krous, Henry F.
author_facet Tee, James B.
Reznik, Vivian
Krous, Henry F.
author_sort Tee, James B.
collection PubMed
description With the expanding use of immunosuppressive therapies and broad-spectrum antibiotics, Candida species has become an increasingly important cause of infections, particularly in the presence of anti-tumor necrosis factor-α therapy. We report the case of a 17-year-old female with ulcerative colitis who developed oliguric renal failure following immunosuppressive and nephrotoxic therapy. Although urine cultures and urinary tract imaging were negative in the face of fungemia, renal biopsy was the key to establishing the diagnosis of fungal tubulo-interstitial nephritis as the primary reversible cause of the renal failure.
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spelling pubmed-26973662009-06-17 Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient Tee, James B. Reznik, Vivian Krous, Henry F. Pediatr Nephrol Brief Report With the expanding use of immunosuppressive therapies and broad-spectrum antibiotics, Candida species has become an increasingly important cause of infections, particularly in the presence of anti-tumor necrosis factor-α therapy. We report the case of a 17-year-old female with ulcerative colitis who developed oliguric renal failure following immunosuppressive and nephrotoxic therapy. Although urine cultures and urinary tract imaging were negative in the face of fungemia, renal biopsy was the key to establishing the diagnosis of fungal tubulo-interstitial nephritis as the primary reversible cause of the renal failure. Springer Berlin Heidelberg 2009-08-01 2009 /pmc/articles/PMC2697366/ /pubmed/19296134 http://dx.doi.org/10.1007/s00467-009-1160-7 Text en © The Author(s) 2009 https://creativecommons.org/licenses/by-nc/2.0/Open AccessThis is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License (https://creativecommons.org/licenses/by-nc/2.0 (https://creativecommons.org/licenses/by-nc/2.0/) ), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Brief Report
Tee, James B.
Reznik, Vivian
Krous, Henry F.
Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient
title Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient
title_full Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient
title_fullStr Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient
title_full_unstemmed Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient
title_short Overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient
title_sort overlapping presentation of fungal tubulointerstitial nephritis in an immunosuppressed pediatric patient
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697366/
https://www.ncbi.nlm.nih.gov/pubmed/19296134
http://dx.doi.org/10.1007/s00467-009-1160-7
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