Cargando…
Investigating the Conformational Stability of Prion Strains through a Kinetic Replication Model
Prion proteins are known to misfold into a range of different aggregated forms, showing different phenotypic and pathological states. Understanding strain specificities is an important problem in the field of prion disease. Little is known about which PrP(Sc) structural properties and molecular mech...
Autores principales: | Zampieri, Mattia, Legname, Giuseppe, Altafini, Claudio |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697384/ https://www.ncbi.nlm.nih.gov/pubmed/19578427 http://dx.doi.org/10.1371/journal.pcbi.1000420 |
Ejemplares similares
-
New insights into structural determinants of prion protein folding and stability
por: Benetti, Federico, et al.
Publicado: (2015) -
Prion and Prion-Like Protein Strains: Deciphering the Molecular Basis of Heterogeneity in Neurodegeneration
por: Scialò, Carlo, et al.
Publicado: (2019) -
mRNA stability and the unfolding of gene expression in the long-period yeast metabolic cycle
por: Soranzo, Nicola, et al.
Publicado: (2009) -
Predicting and characterizing selective multiple drug treatments for metabolic diseases and cancer
por: Facchetti, Giuseppe, et al.
Publicado: (2012) -
Copper coordination modulates prion conversion and infectivity in mammalian prion proteins
por: Legname, Giuseppe
Publicado: (2023)