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Interactions between Cells with Distinct Mutations in c-MYC and Pten in Prostate Cancer
In human somatic tumorigenesis, mutations are thought to arise sporadically in individual cells surrounded by unaffected cells. This contrasts with most current transgenic models where mutations are induced synchronously in entire cell populations. Here we have modeled sporadic oncogene activation u...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697385/ https://www.ncbi.nlm.nih.gov/pubmed/19578399 http://dx.doi.org/10.1371/journal.pgen.1000542 |