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Interactions between Cells with Distinct Mutations in c-MYC and Pten in Prostate Cancer

In human somatic tumorigenesis, mutations are thought to arise sporadically in individual cells surrounded by unaffected cells. This contrasts with most current transgenic models where mutations are induced synchronously in entire cell populations. Here we have modeled sporadic oncogene activation u...

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Detalles Bibliográficos
Autores principales: Kim, Jongchan, Eltoum, Isam-Eldin A., Roh, Meejeon, Wang, Jie, Abdulkadir, Sarki A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697385/
https://www.ncbi.nlm.nih.gov/pubmed/19578399
http://dx.doi.org/10.1371/journal.pgen.1000542