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Structure of the Inhibitor W7 Bound to the Regulatory Domain of Cardiac Troponin C
[Image: see text] The calmodulin antagonist W7 binds to troponin C in the presence of Ca(2+) and inhibits striated muscle contraction. This study integrates multiple data into the structure of the regulatory domain of human cardiac troponin C (cNTnC) bound to Ca(2+) and W7. The protein−W7 interface...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697600/ https://www.ncbi.nlm.nih.gov/pubmed/19419198 http://dx.doi.org/10.1021/bi9001826 |