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ADDME – Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective

The advent of early absorption, distribution, metabolism, excretion, and toxicity (ADMET) screening has increased the attrition rate of weak drug candidates early in the drug-discovery process, and decreased the proportion of compounds failing in clinical trials for ADMET reasons. This paper reviews...

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Detalles Bibliográficos
Autores principales:	Tsaioun, Katya, Bottlaender, Michel, Mabondzo, Aloise
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697629/ https://www.ncbi.nlm.nih.gov/pubmed/19534730 http://dx.doi.org/10.1186/1471-2377-9-S1-S1

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