Cargando…

Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants

In this report, we describe the findings of diffusion MR imaging and proton MR spectroscopy in two infants with acute necrotizing encephalopathy in which there was characteristic symmetrical involvement of the thalami. Diffusion MR images of the lesions showed that the observed apparent diffusion co...

Descripción completa

Detalles Bibliográficos
Autores principales: Goo, Hyun Woo, Choi, Choong-Gon, Yoon, Chong Hyun, Ko, Tae-Sung
Formato: Texto
Lenguaje:English
Publicado: The Korean Radiological Society 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698060/
https://www.ncbi.nlm.nih.gov/pubmed/12679636
http://dx.doi.org/10.3348/kjr.2003.4.1.61
_version_ 1782168364723994624
author Goo, Hyun Woo
Choi, Choong-Gon
Yoon, Chong Hyun
Ko, Tae-Sung
author_facet Goo, Hyun Woo
Choi, Choong-Gon
Yoon, Chong Hyun
Ko, Tae-Sung
author_sort Goo, Hyun Woo
collection PubMed
description In this report, we describe the findings of diffusion MR imaging and proton MR spectroscopy in two infants with acute necrotizing encephalopathy in which there was characteristic symmetrical involvement of the thalami. Diffusion MR images of the lesions showed that the observed apparent diffusion coefficient (ADC) decrease was more prominent in the first patient, who had more severe brain damage and a poorer clinical outcome, than in the second. Proton MR spectroscopy detected an increase in the glutamate/glutamine complex and mobile lipids in the first case but only a small increase of lactate in the second. Diffusion MR imaging and proton MR spectroscopy may provide useful information not only for diagnosis but also for estimating the severity and clinical outcome of acute necrotizing encephalopathy.
format Text
id pubmed-2698060
institution National Center for Biotechnology Information
language English
publishDate 2003
publisher The Korean Radiological Society
record_format MEDLINE/PubMed
spelling pubmed-26980602009-06-23 Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants Goo, Hyun Woo Choi, Choong-Gon Yoon, Chong Hyun Ko, Tae-Sung Korean J Radiol Case Report In this report, we describe the findings of diffusion MR imaging and proton MR spectroscopy in two infants with acute necrotizing encephalopathy in which there was characteristic symmetrical involvement of the thalami. Diffusion MR images of the lesions showed that the observed apparent diffusion coefficient (ADC) decrease was more prominent in the first patient, who had more severe brain damage and a poorer clinical outcome, than in the second. Proton MR spectroscopy detected an increase in the glutamate/glutamine complex and mobile lipids in the first case but only a small increase of lactate in the second. Diffusion MR imaging and proton MR spectroscopy may provide useful information not only for diagnosis but also for estimating the severity and clinical outcome of acute necrotizing encephalopathy. The Korean Radiological Society 2003 2003-03-31 /pmc/articles/PMC2698060/ /pubmed/12679636 http://dx.doi.org/10.3348/kjr.2003.4.1.61 Text en Copyright © 2003 The Korean Radiological Society http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Goo, Hyun Woo
Choi, Choong-Gon
Yoon, Chong Hyun
Ko, Tae-Sung
Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants
title Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants
title_full Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants
title_fullStr Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants
title_full_unstemmed Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants
title_short Acute Necrotizing Encephalopathy: Diffusion MR Imaging and Localized Proton MR Spectroscopic Findings in Two Infants
title_sort acute necrotizing encephalopathy: diffusion mr imaging and localized proton mr spectroscopic findings in two infants
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698060/
https://www.ncbi.nlm.nih.gov/pubmed/12679636
http://dx.doi.org/10.3348/kjr.2003.4.1.61
work_keys_str_mv AT goohyunwoo acutenecrotizingencephalopathydiffusionmrimagingandlocalizedprotonmrspectroscopicfindingsintwoinfants
AT choichoonggon acutenecrotizingencephalopathydiffusionmrimagingandlocalizedprotonmrspectroscopicfindingsintwoinfants
AT yoonchonghyun acutenecrotizingencephalopathydiffusionmrimagingandlocalizedprotonmrspectroscopicfindingsintwoinfants
AT kotaesung acutenecrotizingencephalopathydiffusionmrimagingandlocalizedprotonmrspectroscopicfindingsintwoinfants