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Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US
OBJECTIVE: To determine the findings of various focal hepatic lesions at contrast-enhanced gray-scale ultrasound (US) using a coded harmonic angio (CHA) technique and emphasizing lesion characterization. MATERIALS AND METHODS: The study involved 95 patients with 105 focal hepatic lesions, namely 51...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Radiological Society
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698076/ https://www.ncbi.nlm.nih.gov/pubmed/12845304 http://dx.doi.org/10.3348/kjr.2003.4.2.91 |
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author | Jang, Hyun-Jung Lim, Hyo K. Lee, Won Jae Kim, Seong Hyun Kim, Min Ju Choi, Dongil Lee, Soon Jin Lim, Jae Hoon |
author_facet | Jang, Hyun-Jung Lim, Hyo K. Lee, Won Jae Kim, Seong Hyun Kim, Min Ju Choi, Dongil Lee, Soon Jin Lim, Jae Hoon |
author_sort | Jang, Hyun-Jung |
collection | PubMed |
description | OBJECTIVE: To determine the findings of various focal hepatic lesions at contrast-enhanced gray-scale ultrasound (US) using a coded harmonic angio (CHA) technique and emphasizing lesion characterization. MATERIALS AND METHODS: The study involved 95 patients with 105 focal hepatic lesions, namely 51 hepatocellular carcinomas (HCCs), 22 metastases, 22 hemangiomas, four cases of focal nodular hyperplasia (FNH), and six nontumorous nodules. After the injection of a microbubble contrast agent (SH U 508A), gray-scale harmonic US studies using a CHA technique were performed with a combination of continuous scanning to assess the intratumoral vasculature (vascular imaging) and interval-delay scanning to determine the sequential enhancement pattern (acoustic emission imaging). Each imaging pattern was categorized and analyzed. RESULTS: At vascular imaging, 69% of HCCs (35/51) showed irregular branching vessels, while in 91% of metastases (20/22) a peripherally stippled pattern was observed. Intratumoral vessels were absent in 95% of hemangiomas (21/22) and all nontumorous lesions (6/6), while in 75% of FNHs (3/4) a spoke-wheel pattern was evident. At acoustic emission imaging, 71% of HCCs (36/51) showed heterogeneous enhancement and 86% (19/22) of metastases showed rim- or flame-like peripheral enhancement during the early phase, with washout occurring in all HCCs and metastases (100%, 73/73) during the late phase. In hemangiomas, enhancement was either peripheral and nodular (19/22, 86%) or persistent and homogeneous (3/22, 14%), and 75% of FNHs (3/4) became isoechoic during the late phase. CONCLUSION: At contrast-enhanced gray-scale US using a CHA technique, a period of continuous scanning depicted the intratumoral vasculature, and interval-delay scanning demonstrated the sequential enhancement pattern. The characteristic findings of various focal hepatic lesions were thus determined. |
format | Text |
id | pubmed-2698076 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | The Korean Radiological Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-26980762009-06-23 Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US Jang, Hyun-Jung Lim, Hyo K. Lee, Won Jae Kim, Seong Hyun Kim, Min Ju Choi, Dongil Lee, Soon Jin Lim, Jae Hoon Korean J Radiol Original Article OBJECTIVE: To determine the findings of various focal hepatic lesions at contrast-enhanced gray-scale ultrasound (US) using a coded harmonic angio (CHA) technique and emphasizing lesion characterization. MATERIALS AND METHODS: The study involved 95 patients with 105 focal hepatic lesions, namely 51 hepatocellular carcinomas (HCCs), 22 metastases, 22 hemangiomas, four cases of focal nodular hyperplasia (FNH), and six nontumorous nodules. After the injection of a microbubble contrast agent (SH U 508A), gray-scale harmonic US studies using a CHA technique were performed with a combination of continuous scanning to assess the intratumoral vasculature (vascular imaging) and interval-delay scanning to determine the sequential enhancement pattern (acoustic emission imaging). Each imaging pattern was categorized and analyzed. RESULTS: At vascular imaging, 69% of HCCs (35/51) showed irregular branching vessels, while in 91% of metastases (20/22) a peripherally stippled pattern was observed. Intratumoral vessels were absent in 95% of hemangiomas (21/22) and all nontumorous lesions (6/6), while in 75% of FNHs (3/4) a spoke-wheel pattern was evident. At acoustic emission imaging, 71% of HCCs (36/51) showed heterogeneous enhancement and 86% (19/22) of metastases showed rim- or flame-like peripheral enhancement during the early phase, with washout occurring in all HCCs and metastases (100%, 73/73) during the late phase. In hemangiomas, enhancement was either peripheral and nodular (19/22, 86%) or persistent and homogeneous (3/22, 14%), and 75% of FNHs (3/4) became isoechoic during the late phase. CONCLUSION: At contrast-enhanced gray-scale US using a CHA technique, a period of continuous scanning depicted the intratumoral vasculature, and interval-delay scanning demonstrated the sequential enhancement pattern. The characteristic findings of various focal hepatic lesions were thus determined. The Korean Radiological Society 2003 2003-06-30 /pmc/articles/PMC2698076/ /pubmed/12845304 http://dx.doi.org/10.3348/kjr.2003.4.2.91 Text en Copyright © 2003 The Korean Radiological Society http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Jang, Hyun-Jung Lim, Hyo K. Lee, Won Jae Kim, Seong Hyun Kim, Min Ju Choi, Dongil Lee, Soon Jin Lim, Jae Hoon Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US |
title | Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US |
title_full | Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US |
title_fullStr | Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US |
title_full_unstemmed | Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US |
title_short | Focal Hepatic Lesions: Evaluation with Contrast-Enhanced Gray-Scale Harmonic US |
title_sort | focal hepatic lesions: evaluation with contrast-enhanced gray-scale harmonic us |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698076/ https://www.ncbi.nlm.nih.gov/pubmed/12845304 http://dx.doi.org/10.3348/kjr.2003.4.2.91 |
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