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Low-Abundance HIV Drug-Resistant Viral Variants in Treatment-Experienced Persons Correlate with Historical Antiretroviral Use
BACKGROUND: It is largely unknown how frequently low-abundance HIV drug-resistant variants at levels under limit of detection of conventional genotyping (<20% of quasi-species) are present in antiretroviral-experienced persons experiencing virologic failure. Further, the clinical implications of...
Autores principales: | Le, Thuy, Chiarella, Jennifer, Simen, Birgitte B., Hanczaruk, Bozena, Egholm, Michael, Landry, Marie L., Dieckhaus, Kevin, Rosen, Marc I., Kozal, Michael J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698118/ https://www.ncbi.nlm.nih.gov/pubmed/19562031 http://dx.doi.org/10.1371/journal.pone.0006079 |
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