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Chemical Genetics Reveals Bacterial and Host Cell Functions Critical for Type IV Effector Translocation by Legionella pneumophila

Delivery of effector proteins is a process widely used by bacterial pathogens to subvert host cell functions and cause disease. Effector delivery is achieved by elaborate injection devices and can often be triggered by environmental stimuli. However, effector export by the L. pneumophila Icm/Dot Typ...

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Detalles Bibliográficos
Autores principales: Charpentier, Xavier, Gabay, Joëlle E., Reyes, Moraima, Zhu, Jing W., Weiss, Arthur, Shuman, Howard A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698123/
https://www.ncbi.nlm.nih.gov/pubmed/19578436
http://dx.doi.org/10.1371/journal.ppat.1000501