Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man

Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm(3), and in...

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Autores principales: Yoganathan, Kathir, Austin, Michael
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698697/
https://www.ncbi.nlm.nih.gov/pubmed/19668413
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author Yoganathan, Kathir
Austin, Michael
author_facet Yoganathan, Kathir
Austin, Michael
author_sort Yoganathan, Kathir
collection PubMed
description Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm(3), and in these circumstances clinicians are likely to consider commencing anti-CMV therapy without considering other causes. We report a man with HIV who developed bilateral retinal hemorrhages and ischemic maculopathy in association with zidovudine (AZT)-induced anemia. Retinal hemorrhages resolved following blood transfusion.
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spelling pubmed-26986972009-08-10 Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man Yoganathan, Kathir Austin, Michael Clin Ophthalmol Case Report Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm(3), and in these circumstances clinicians are likely to consider commencing anti-CMV therapy without considering other causes. We report a man with HIV who developed bilateral retinal hemorrhages and ischemic maculopathy in association with zidovudine (AZT)-induced anemia. Retinal hemorrhages resolved following blood transfusion. Dove Medical Press 2008-03 /pmc/articles/PMC2698697/ /pubmed/19668413 Text en © 2008 Yoganathan and Austin, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Case Report
Yoganathan, Kathir
Austin, Michael
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_full Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_fullStr Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_full_unstemmed Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_short Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_sort ischemic maculopathy in zidovudine-induced anemia in an hiv-positive man
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698697/
https://www.ncbi.nlm.nih.gov/pubmed/19668413
work_keys_str_mv AT yoganathankathir ischemicmaculopathyinzidovudineinducedanemiainanhivpositiveman
AT austinmichael ischemicmaculopathyinzidovudineinducedanemiainanhivpositiveman

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