Identification of novel Notch target genes in T cell leukaemia

BACKGROUND: Dysregulated Notch signalling is believed to play an important role in the development and maintenance of T cell leukaemia. At a cellular level, Notch signalling promotes proliferation and inhibits apoptosis of T cell acute lymphoblastic leukaemia (T-ALL) cells. In this study we aimed to...

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Detalles Bibliográficos
Autores principales: Chadwick, Nicholas, Zeef, Leo, Portillo, Virginia, Fennessy, Carl, Warrander, Fiona, Hoyle, Sarah, Buckle, Anne-Marie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698846/
https://www.ncbi.nlm.nih.gov/pubmed/19508709
http://dx.doi.org/10.1186/1476-4598-8-35

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