T-cell epitope polymorphisms of the Plasmodium falciparum circumsporozoite protein among field isolates from Sierra Leone: age-dependent haplotype distribution?

BACKGROUND: In the context of the development of a successful malaria vaccine, understanding the polymorphisms exhibited by malaria antigens in natural parasite populations is crucial for proper vaccine design. Recent observations have indicated that sequence polymorphisms in the C-terminal T-cell e...

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Detalles Bibliográficos
Autores principales: Jalloh, Amadu, Jalloh, Muctarr, Matsuoka, Hiroyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698914/
https://www.ncbi.nlm.nih.gov/pubmed/19500348
http://dx.doi.org/10.1186/1475-2875-8-120

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