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IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells

BACKGROUND: Colorectal cancer is the third most common cancer in the western world. Chemotherapy is often ineffective to treat the advanced colorectal cancers due to the chemo-resistance. A major contributor to chemo-resistance is tumour-derived inhibition or avoidance of apoptosis. Insulin-like gro...

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Detalles Bibliográficos
Autores principales:	Yang, Shi Yu, Bolvin, Capucine, Sales, Kevin M, Fuller, Barry, Seifalian, Alexander M, Winslet, Marc C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698923/ https://www.ncbi.nlm.nih.gov/pubmed/19460165 http://dx.doi.org/10.1186/1471-2407-9-158

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