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Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situ hybridization (FISH): pathologist assessment compared to quantitative image analysis

BACKGROUND: In breast cancer patients, HER2 overexpression is routinely assessed by immunohistochemistry (IHC) and equivocal cases are subject to fluorescent in situ hybridization (FISH). Our study compares HER2 scoring by histopathologists with automated quantitation of staining, and determines the...

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Detalles Bibliográficos
Autores principales:	Turashvili, Gulisa, Leung, Samuel, Turbin, Dmitry, Montgomery, Kelli, Gilks, Blake, West, Rob, Carrier, Melinda, Huntsman, David, Aparicio, Samuel
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698924/ https://www.ncbi.nlm.nih.gov/pubmed/19476653 http://dx.doi.org/10.1186/1471-2407-9-165

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