Cargando…

Chondromodulin-1 directly suppresses growth of human cancer cells

BACKGROUND: Chondromodulin-1 (ChM1), an endogenous anti-angiogenic factor expressed in cartilage, has been suggested to inhibit invasion of endothelial cells into cartilage. In addition, the ectopic administration of ChM1 has been reported to suppress tumorigenesis in vivo. However, it is unclear wh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mera, Hisashi, Kawashima, Hiroyuki, Yoshizawa, Tatsuya, Ishibashi, Osamu, Ali, Md Moksed, Hayami, Tadashi, Kitahara, Hiroshi, Yamagiwa, Hiroshi, Kondo, Naoki, Ogose, Akira, Endo, Naoto
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698925/ https://www.ncbi.nlm.nih.gov/pubmed/19480713 http://dx.doi.org/10.1186/1471-2407-9-166

Ejemplares similares

The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3
por: Kanai, Tomotake, et al.
Publicado: (2020)

＜Editors’ Choice＞ Stanniocalcin-1 mRNA expression in soft-tissue tumors
por: Yamagishi, Tetsuro, et al.
Publicado: (2020)

Experimental arthritis and Porphyromonas gingivalis administration synergistically decrease bone regeneration in femoral cortical defects
por: Okumura, Go, et al.
Publicado: (2019)

The natural history of incidental retroperitoneal schwannomas
por: Ogose, Akira, et al.
Publicado: (2019)

Significantly earlier ambulation and reduced risk of near-falls with continuous infusion nerve blocks: a retrospective pilot study of adductor canal block compared to femoral nerve block in total knee arthroplasty
por: Fujita, Yutaka, et al.
Publicado: (2022)

Receptor-Activator of Nuclear KappaB Ligand Expression as a New Therapeutic Target in Primary Bone Tumors
por: Yamagishi, Tetsuro, et al.
Publicado: (2016)

Multinucleation followed by an acytokinetic cell division in myxofibrosarcoma with giant cell proliferation
por: Ariizumi, Takashi, et al.
Publicado: (2009)

Prognostic impact of the tumor immune microenvironment in synovial sarcoma
por: Oike, Naoki, et al.
Publicado: (2018)

Frequent expression of human leukocyte antigen class I and the status of intratumoral immune cells in alveolar soft part sarcoma
por: Ogose, Akira, et al.
Publicado: (2017)

Malignant transformation of fibrous dysplasia: A case report
por: HATANO, HIROSHI, et al.
Publicado: (2014)

Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas
por: Oike, Naoki, et al.
Publicado: (2021)

Denosumab as a potential therapeutic option for leiomyosarcoma with osteoclast-like giant cells: A case report
por: Sasaki, Taro, et al.
Publicado: (2018)

A malignant solitary fibrous tumour arising from the first lumbar vertebra and mimicking an osteosarcoma: a case report
por: Oike, Naoki, et al.
Publicado: (2017)

Real-time polymerase chain reaction analysis of MDM2 and CDK4 expression using total RNA from core-needle biopsies is useful for diagnosing adipocytic tumors
por: Sasaki, Taro, et al.
Publicado: (2014)

Chondromodulin is necessary for cartilage callus distraction in mice
por: Yukata, Kiminori, et al.
Publicado: (2023)

Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease
por: Zhu, Sipin, et al.
Publicado: (2019)

Comparison of post-operative three-dimensional and two-dimensional evaluation of component position for total knee arthroplasty
por: Tanifuji, Osamu, et al.
Publicado: (2021)

Synthetic disulfide-bridged cyclic peptides mimic the anti-angiogenic actions of chondromodulin-I
por: Miura, Shigenori, et al.
Publicado: (2012)

Localization of chondromodulin-I at the feto-maternal interface and its inhibitory actions on trophoblast invasion in vitro
por: Miura, Shigenori, et al.
Publicado: (2011)

Dual Roles of Ascidian Chondromodulin-1: Promoting Cell Proliferation Whilst Suppressing the Growth of Tumor Cells
por: Dou, Xiaoju, et al.
Publicado: (2018)

The N-Terminal Cleavage of Chondromodulin-I in Growth-Plate Cartilage at the Hypertrophic and Calcified Zones during Bone Development
por: Miura, Shigenori, et al.
Publicado: (2014)

The physiological and pathological properties of Mead acid, an endogenous multifunctional n-9 polyunsaturated fatty acid
por: Kawashima, Hiroshi, et al.
Publicado: (2023)

Disrupted Bone Metabolism in Long-Term Bedridden Patients
por: Eimori, Keiko, et al.
Publicado: (2016)

Effectiveness of 4-1BB-costimulated HER2-targeted chimeric antigen receptor T cell therapy for synovial sarcoma
por: Murayama, Yudai, et al.
Publicado: (2021)

Increased incidence among the very elderly in the 2020 Niigata Prefecture Osteoporotic Hip Fracture Study
por: Nozaki, Asami, et al.
Publicado: (2023)

Ankle arthrodesis using a retrograde intramedullary rod with fins for highly destructive joints in elderly patients with rheumatoid arthritis: A report of two cases
por: Takahashi, Shun, et al.
Publicado: (2022)

Thinner femoral cortical thickness in patients with destructive rheumatoid arthritis of the knee
por: Kakutani, Rika, et al.
Publicado: (2023)

Carbonic anhydrase 3 increases during liver adipogenesis even in pre‐obesity, and its inhibitors reduce liver adipose accumulation
por: Yamamoto, Hiroyuki, et al.
Publicado: (2022)

Point-of-Care Ultrasound for Mimicker Lesions of Incarcerated Inguinal Hernia
por: Hosokawa, Takahiro, et al.
Publicado: (2023)

Association between asymptomatic hyperuricemia and new-onset chronic kidney disease in Japanese male workers: a long-term retrospective cohort study
por: Kawashima, Masatoshi, et al.
Publicado: (2011)

The Role of Heat Shock Response in Insulin Resistance and Diabetes
por: Kondo, Tatsuya, et al.
Publicado: (2014)

Correlation between posterior tibial slope and sagittal alignment under weight-bearing conditions in osteoarthritic knees
por: Mochizuki, Tomoharu, et al.
Publicado: (2018)

Urinary levels of Hepatocarcinoma-intestine-pancreas/Pancreatitis-associated protein as a diagnostic biomarker in patients with bladder cancer
por: Nitta, Yujiro, et al.
Publicado: (2012)

NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma
por: Murayama, Yudai, et al.
Publicado: (2022)

T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer
por: Xue, Busheng, et al.
Publicado: (2022)

Dual inhibition of the MEK/ERK and PI3K/AKT pathways prevents pulmonary GVHD suppressing perivenulitis and bronchiolitis
por: Muranushi, Hiroyuki, et al.
Publicado: (2022)

Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in vivo through suppression of PDGFR-β
por: Ohishi, Jun, et al.
Publicado: (2013)

Rhododendrol, a reductive metabolite of raspberry ketone, suppresses the differentiation of 3T3‑L1 cells into adipocytes
por: Uramaru, Naoto, et al.
Publicado: (2023)

Low phonon energies and wideband optical windows of La(2)O(3)-Ga(2)O(3) glasses prepared using an aerodynamic levitation technique
por: Yoshimoto, Kohei, et al.
Publicado: (2017)

Intake of arachidonic acid-containing lipids in adult humans: dietary surveys and clinical trials
por: Kawashima, Hiroshi
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kfkpev01hvtufdt68afktvdnu9