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Quantification of Normal Cell Fraction and Copy Number Neutral LOH in Clinical Lung Cancer Samples Using SNP Array Data
BACKGROUND: Technologies based on DNA microarrays have the potential to provide detailed information on genomic aberrations in tumor cells. In practice a major obstacle for quantitative detection of aberrations is the heterogeneity of clinical tumor tissue. Since tumor tissue invariably contains gen...
Autores principales: | Göransson, Hanna, Edlund, Karolina, Rydåker, Maria, Rasmussen, Markus, Winquist, Johan, Ekman, Simon, Bergqvist, Michael, Thomas, Andrew, Lambe, Mats, Rosenquist, Richard, Holmberg, Lars, Micke, Patrick, Botling, Johan, Isaksson, Anders |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699026/ https://www.ncbi.nlm.nih.gov/pubmed/19557126 http://dx.doi.org/10.1371/journal.pone.0006057 |
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