Dll1 Haploinsufficiency in Adult Mice Leads to a Complex Phenotype Affecting Metabolic and Immunological Processes

BACKGROUND: The Notch signaling pathway is an evolutionary conserved signal transduction pathway involved in embryonic patterning and regulation of cell fates during development and self-renewal. Recent studies have demonstrated that this pathway is integral to a complex system of interactions, invo...

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Detalles Bibliográficos
Autores principales: Rubio-Aliaga, Isabel, Przemeck, Gerhard K. H., Fuchs, Helmut, Gailus-Durner, Valérie, Adler, Thure, Hans, Wolfgang, Horsch, Marion, Rathkolb, Birgit, Rozman, Jan, Schrewe, Anja, Wagner, Sibylle, Hoelter, Sabine M., Becker, Lore, Klopstock, Thomas, Wurst, Wolfgang, Wolf, Eckhard, Klingenspor, Martin, Ivandic, Boris T., Busch, Dirk H., Beckers, Johannes, Hrabé de Angelis, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699037/
https://www.ncbi.nlm.nih.gov/pubmed/19562077
http://dx.doi.org/10.1371/journal.pone.0006054

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