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Emerging trends in plasma‐free manufacturing of recombinant protein therapeutics expressed in mammalian cells
Mammalian cells are the expression system of choice for therapeutic proteins, especially those requiring complex post‐translational modifications. Traditionally, these cells are grown in medium supplemented with serum and other animal‐ or human‐derived components to support viability and productivit...
Autores principales: | Grillberger, Leopold, Kreil, Thomas R., Nasr, Sonia, Reiter, Manfred |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
WILEY‐VCH Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699044/ https://www.ncbi.nlm.nih.gov/pubmed/19226552 http://dx.doi.org/10.1002/biot.200800241 |
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