State-dependent modulation of CFTR gating by pyrophosphate

Cystic fibrosis transmembrane conductance regulator (CFTR) is an adenosine triphosphate (ATP)-gated chloride channel. ATP-induced dimerization of CFTR's two nucleotide-binding domains (NBDs) has been shown to reflect the channel open state, whereas hydrolysis of ATP is associated with channel c...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Feng, Shimizu, Hiroyasu, Sohma, Yoshiro, Li, Min, Hwang, Tzyh-Chang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699106/
https://www.ncbi.nlm.nih.gov/pubmed/19332621
http://dx.doi.org/10.1085/jgp.200810186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699106/
https://www.ncbi.nlm.nih.gov/pubmed/19332621
http://dx.doi.org/10.1085/jgp.200810186

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