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Drug Discovery Using Chemical Systems Biology: Repositioning the Safe Medicine Comtan to Treat Multi-Drug and Extensively Drug Resistant Tuberculosis
The rise of multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis around the world, including in industrialized nations, poses a great threat to human health and defines a need to develop new, effective and inexpensive anti-tubercular agents. Previously we developed a chemical...
Autores principales: | Kinnings, Sarah L., Liu, Nina, Buchmeier, Nancy, Tonge, Peter J., Xie, Lei, Bourne, Philip E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699117/ https://www.ncbi.nlm.nih.gov/pubmed/19578428 http://dx.doi.org/10.1371/journal.pcbi.1000423 |
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