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A novel myelin P0–specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy
Autoimmune-prone nonobese diabetic mice deficient for B7-2 spontaneously develop an autoimmune peripheral neuropathy mediated by inflammatory CD4(+) T cells that is reminiscent of Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy. To determine the etiology of this disease...
Autores principales: | Louvet, Cédric, Kabre, Beniwende G., Davini, Dan W., Martinier, Nicolas, Su, Maureen A., DeVoss, Jason J., Rosenthal, Wendy L., Anderson, Mark S., Bour-Jordan, Hélène, Bluestone, Jeffrey A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699118/ https://www.ncbi.nlm.nih.gov/pubmed/19221395 http://dx.doi.org/10.1084/jem.20082113 |
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