Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

The C-type lectin-like receptor CD161, which has recently been described to promote T cell expansion, is expressed on a discrete subset of human CD4 T cells. The function of such cells, however, has remained elusive. We now demonstrate that CD161(+) CD4 T cells comprise a circulating and gut-residen...

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Detalles Bibliográficos
Autores principales: Kleinschek, Melanie A., Boniface, Katia, Sadekova, Svetlana, Grein, Jeff, Murphy, Erin E., Turner, Scott P., Raskin, Lisa, Desai, Bela, Faubion, William A., de Waal Malefyt, Rene, Pierce, Robert H., McClanahan, Terrill, Kastelein, Robert A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699125/
https://www.ncbi.nlm.nih.gov/pubmed/19273624
http://dx.doi.org/10.1084/jem.20081712

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