In search of nonribosomal nucleolar protein function and regulation

The life of the nucleolus has proven to be more colorful and multifaceted than had been envisioned a decade ago. A large number of proteins found in this subnuclear compartment have no identifiable tie either to the ribosome biosynthetic pathway or to the other newly established activities occurring...

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Detalles Bibliográficos
Autores principales: Pederson, Thoru, Tsai, Robert Y.L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699146/
https://www.ncbi.nlm.nih.gov/pubmed/19289796
http://dx.doi.org/10.1083/jcb.200812014
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author Pederson, Thoru
Tsai, Robert Y.L.
author_facet Pederson, Thoru
Tsai, Robert Y.L.
author_sort Pederson, Thoru
collection PubMed
description The life of the nucleolus has proven to be more colorful and multifaceted than had been envisioned a decade ago. A large number of proteins found in this subnuclear compartment have no identifiable tie either to the ribosome biosynthetic pathway or to the other newly established activities occurring within the nucleolus. The questions of how and why these proteins end up in this subnuclear compartment remain unanswered and are the focus of intense current interest. This review discusses our thoughts on the discovery of nonribosomal proteins in the nucleolus.
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spelling pubmed-26991462009-09-23 In search of nonribosomal nucleolar protein function and regulation Pederson, Thoru Tsai, Robert Y.L. J Cell Biol Reviews The life of the nucleolus has proven to be more colorful and multifaceted than had been envisioned a decade ago. A large number of proteins found in this subnuclear compartment have no identifiable tie either to the ribosome biosynthetic pathway or to the other newly established activities occurring within the nucleolus. The questions of how and why these proteins end up in this subnuclear compartment remain unanswered and are the focus of intense current interest. This review discusses our thoughts on the discovery of nonribosomal proteins in the nucleolus. The Rockefeller University Press 2009-03-23 /pmc/articles/PMC2699146/ /pubmed/19289796 http://dx.doi.org/10.1083/jcb.200812014 Text en © 2009 Pederson and Tsai This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Pederson, Thoru
Tsai, Robert Y.L.
In search of nonribosomal nucleolar protein function and regulation
title In search of nonribosomal nucleolar protein function and regulation
title_full In search of nonribosomal nucleolar protein function and regulation
title_fullStr In search of nonribosomal nucleolar protein function and regulation
title_full_unstemmed In search of nonribosomal nucleolar protein function and regulation
title_short In search of nonribosomal nucleolar protein function and regulation
title_sort in search of nonribosomal nucleolar protein function and regulation
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699146/
https://www.ncbi.nlm.nih.gov/pubmed/19289796
http://dx.doi.org/10.1083/jcb.200812014
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AT tsairobertyl insearchofnonribosomalnucleolarproteinfunctionandregulation

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