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A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover

HECT (homologous to the E6AP C terminus) ubiquitin ligases have diverse functions in eukaryotic cells. In screens for proteins that bind to the HECT ubiquitin ligase WWP1, we identified Spartin, which is also known as SPG20. This protein is truncated in a neurological disease, Troyer syndrome. In th...

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Detalles Bibliográficos
Autores principales: Eastman, Scott W., Yassaee, Mina, Bieniasz, Paul D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699154/
https://www.ncbi.nlm.nih.gov/pubmed/19307600
http://dx.doi.org/10.1083/jcb.200808041

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