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Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery

The evolutionarily conserved protein Sem1/Dss1 is a subunit of the regulatory particle (RP) of the proteasome, and, in mammalian cells, binds the tumor suppressor protein BRCA2. Here, we describe a new function for yeast Sem1. We show that sem1 mutants are impaired in messenger RNA (mRNA) export and...

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Detalles Bibliográficos
Autores principales:	Faza, Marius Boulos, Kemmler, Stefan, Jimeno, Sonia, González-Aguilera, Cristina, Aguilera, Andrés, Hurt, Ed, Panse, Vikram Govind
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2009
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699155/ https://www.ncbi.nlm.nih.gov/pubmed/19289793 http://dx.doi.org/10.1083/jcb.200810059

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