Delivery of sry1, but not sry2, to the kidney increases blood pressure and sns indices in normotensive wky rats

BACKGROUND: Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats with the SHR Y chromosome (SHR/y rat). A candidate for this Y chromosome hypertension locus is Sry, a gene that encodes a transcription factor responsible for testes...

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Detalles Bibliográficos
Autores principales: Ely, Daniel, Milsted, Amy, Dunphy, Gail, Boehme, Shannon, Dunmire, Jeff, Hart, Mike, Toot, Jonathon, Martins, Almir, Turner, Monte
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699329/
https://www.ncbi.nlm.nih.gov/pubmed/19500370
http://dx.doi.org/10.1186/1472-6793-9-10

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