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Genetic variants in FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study

BACKGROUND: The human fibroblast growth factor (FGF) and its receptor (FGFR) play an important role in tumorigenesis. Deregulation of the FGFR2 gene has been identified in a number of cancer sites. Overexpression of the FGFR4 protein has been linked to cutaneous melanoma progression. Previous studie...

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Detalles Bibliográficos
Autores principales: Nan, Hongmei, Qureshi, Abrar A, Hunter, David J, Han, Jiali
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699349/
https://www.ncbi.nlm.nih.gov/pubmed/19500394
http://dx.doi.org/10.1186/1471-2407-9-172