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Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy

Complex regulation of T cell functions during pregnancy is required to ensure materno-fetal tolerance. Here we reveal a novel pathway for the temporary suppression of maternal T cell responses in uncomplicated human pregnancies. Our results show that arginase activity is significantly increased in t...

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Detalles Bibliográficos
Autores principales:	Kropf, Pascale, Baud, David, Marshall, Sara E, Munder, Markus, Mosley, Angelina, Fuentes, José M, Bangham, Charles R M, Taylor, Graham P, Herath, Shanti, Choi, Beak-San, Soler, Germán, Teoh, Tg, Modolell, Manuel, Müller, Ingrid
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2007
Materias:	Cellular immune response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699382/ https://www.ncbi.nlm.nih.gov/pubmed/17330821 http://dx.doi.org/10.1002/eji.200636542

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