Cargando…

Adenosine closes the K(+) channel K(Ca)3.1 in human lung mast cells and inhibits their migration via the adenosine A(2A) receptor

Human lung mast cells (HLMC) express the Ca(2+)-activated K(+) channel K(Ca)3.1, which opens following IgE-dependent activation. This hyperpolarises the cell membrane and potentiates both Ca(2+) influx and degranulation. In addition, blockade of K(Ca)3.1 profoundly inhibits HLMC migration to a varie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duffy, S Mark, Cruse, Glenn, Brightling, Christopher E, Bradding, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2007
Materias:	Leukocyte signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699420/ https://www.ncbi.nlm.nih.gov/pubmed/17474152 http://dx.doi.org/10.1002/eji.200637024

Ejemplares similares

Engagement of the EP(2) prostanoid receptor closes the K(+) channel K(Ca)3.1 in human lung mast cells and attenuates their migration
por: Duffy, S Mark, et al.
Publicado: (2008)

Functional K(Ca)3.1 K(+) channels are required for human fibrocyte migration
por: Cruse, Glenn, et al.
Publicado: (2011)

Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization
por: Glanville, Stephanie H, et al.
Publicado: (2009)

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
por: Oliveira, Marta I, et al.
Publicado: (2012)

Orai/CRACM1 and K(Ca)3.1 ion channels interact in the human lung mast cell plasma membrane
por: Duffy, S. Mark, et al.
Publicado: (2015)

The K(+) Channel K(Ca)3.1 as a Novel Target for Idiopathic Pulmonary Fibrosis
por: Roach, Katy Morgan, et al.
Publicado: (2013)

K(Ca)3.1 K(+) Channel Expression and Function in Human Bronchial Epithelial Cells
por: Arthur, Greer K., et al.
Publicado: (2015)

Correction: The K(+) Channel K(Ca)3.1 as a Novel Target for Idiopathic Pulmonary Fibrosis
por: Roach, Katy M, et al.
Publicado: (2014)

Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and K(Ca)3.1 ion channels, but involves phosphoinositide 3-kinase
por: Cortés Franco, Klaus-Daniel, et al.
Publicado: (2022)

Recruitment of a Cytoplasmic Chaperone Relay by the A(2A) Adenosine Receptor
por: Bergmayr, Christian, et al.
Publicado: (2013)

Reengineering the Collision Coupling and Diffusion Mode of the A(2A)-adenosine Receptor: PALMITOYLATION IN HELIX 8 RELIEVES CONFINEMENT
por: Keuerleber, Simon, et al.
Publicado: (2012)

Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by K(Ca)3.1 K(+) channels
por: Roach, Katy M, et al.
Publicado: (2015)

Adenosine stimulates the basolateral 50 pS K(+) channel in renal proximal tubule via adenosine-A1 receptor
por: Liu, Hao, et al.
Publicado: (2023)

Insulin Restores Gestational Diabetes Mellitus–Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium
por: Westermeier, Francisco, et al.
Publicado: (2011)

Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors
por: Melick, Chase H., et al.
Publicado: (2020)

IgE alone promotes human lung mast cell survival through the autocrine production of IL-6
por: Cruse, Glenn, et al.
Publicado: (2008)

Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells
por: Karrich, Julien J., et al.
Publicado: (2018)

SAT-038 Physiology of Mice Lacking All Four Adenosine Receptors
por: Xiao, Cuiying, et al.
Publicado: (2019)

Airway smooth muscle proliferation and survival is not modulated by mast cells
por: Kaur, D, et al.
Publicado: (2010)

K(Ca)3.1 Channel-Blockade Attenuates Airway Pathophysiology in a Sheep Model of Chronic Asthma
por: Van Der Velden, Joanne, et al.
Publicado: (2013)

Role of Mast Cell-Derived Adenosine in Cancer
por: Gorzalczany, Yaara, et al.
Publicado: (2019)

Adenosine Signaling in Mast Cells and Allergic Diseases
por: Garcia-Garcia, Lucia, et al.
Publicado: (2021)

The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca(2+)-activated large-conductance K(+) channels in endothelial cells
por: Bondarenko, Alexander I., et al.
Publicado: (2010)

TRIM31 promotes acute myeloid leukemia progression and sensitivity to daunorubicin through the Wnt/β-catenin signaling
por: Xiao, Yi, et al.
Publicado: (2020)

Mast Cell Adenosine Receptors Function: A Focus on the A3 Adenosine Receptor and Inflammation
por: Rudich, Noam, et al.
Publicado: (2012)

A Two-state Model for the Diffusion of the A(2A) Adenosine Receptor in Hippocampal Neurons: AGONIST-INDUCED SWITCH TO SLOW MOBILITY IS MODIFIED BY SYNAPSE-ASSOCIATED PROTEIN 102 (SAP102)
por: Thurner, Patrick, et al.
Publicado: (2014)

Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T‐cell migration across the blood–brain barrier under flow in vitro
por: Rudolph, Henriette, et al.
Publicado: (2016)

The bare necessities of plant K(+) channel regulation
por: Lefoulon, Cécile
Publicado: (2021)

Cancer-Associated Intermediate Conductance Ca(2+)-Activated K(+) Channel K(Ca)3.1
por: Mohr, Corinna J., et al.
Publicado: (2019)

K(Ca)2 and K(Ca)3.1 Channels in the Airways: A New Therapeutic Target
por: Orfali, Razan, et al.
Publicado: (2023)

Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels
por: Proks, Peter, et al.
Publicado: (2016)

K(Ca)3.1 Channels and Glioblastoma: In Vitro Studies
por: Klumpp, Lukas, et al.
Publicado: (2018)

The Contribution of Orai(CRACM)1 and Orai(CRACM)2 Channels in Store-Operated Ca(2+) Entry and Mediator Release in Human Lung Mast Cells
por: Ashmole, Ian, et al.
Publicado: (2013)

Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of K(Ca)2.x and K(Ca)3.1 Channels
por: Kloza, Monika, et al.
Publicado: (2019)

Correction to ‘Running out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channels’
por: Proks, Peter, et al.
Publicado: (2016)

Leptin-dependent Phosphorylation of PTEN Mediates Actin Restructuring and Activation of ATP-sensitive K(+) Channels
por: Ning, Ke, et al.
Publicado: (2009)

Inhibition of HERG1 K(+) channel protein expression decreases cell proliferation of human small cell lung cancer cells
por: Glassmeier, Günter, et al.
Publicado: (2011)

Endoplasmic reticulum Ca(2+) release causes Rieske iron–sulfur protein-mediated mitochondrial ROS generation in pulmonary artery smooth muscle cells
por: Dong, Dapeng, et al.
Publicado: (2019)

IL-4 Amplifies the Pro-Inflammatory Effect of Adenosine in Human Mast Cells by Changing Expression Levels of Adenosine Receptors
por: Hua, Xiaoyang, et al.
Publicado: (2011)

An NAADP-gated Two-pore Channel Targeted to the Plasma Membrane Uncouples Triggering from Amplifying Ca(2+) Signals
por: Brailoiu, Eugen, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ib9kmdr2ps1jg2h0pv7kamu4sk