Cargando…

Engagement of the EP(2) prostanoid receptor closes the K(+) channel K(Ca)3.1 in human lung mast cells and attenuates their migration

Human lung mast cells (HLMC) express the Ca(2+)-activated K(+) channel K(Ca)3.1, which plays a crucial role in their migration to a variety of diverse chemotactic stimuli. K(Ca)3.1 activation is attenuated by the β(2)-adrenoceptor and the adenosine A(2A) receptor through a G(s)-coupled mechanism ind...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duffy, S Mark, Cruse, Glenn, Cockerill, Sarah L, Brightling, Chris E, Bradding, Peter
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2008
Materias:	Leukocyte signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699428/ https://www.ncbi.nlm.nih.gov/pubmed/18792407 http://dx.doi.org/10.1002/eji.200738106

Ejemplares similares

Adenosine closes the K(+) channel K(Ca)3.1 in human lung mast cells and inhibits their migration via the adenosine A(2A) receptor
por: Duffy, S Mark, et al.
Publicado: (2007)

CD6 attenuates early and late signaling events, setting thresholds for T-cell activation
por: Oliveira, Marta I, et al.
Publicado: (2012)

Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization
por: Glanville, Stephanie H, et al.
Publicado: (2009)

Functional K(Ca)3.1 K(+) channels are required for human fibrocyte migration
por: Cruse, Glenn, et al.
Publicado: (2011)

Orai/CRACM1 and K(Ca)3.1 ion channels interact in the human lung mast cell plasma membrane
por: Duffy, S. Mark, et al.
Publicado: (2015)

IgE alone promotes human lung mast cell survival through the autocrine production of IL-6
por: Cruse, Glenn, et al.
Publicado: (2008)

The K(+) Channel K(Ca)3.1 as a Novel Target for Idiopathic Pulmonary Fibrosis
por: Roach, Katy Morgan, et al.
Publicado: (2013)

Correction: The K(+) Channel K(Ca)3.1 as a Novel Target for Idiopathic Pulmonary Fibrosis
por: Roach, Katy M, et al.
Publicado: (2014)

K(Ca)3.1 K(+) Channel Expression and Function in Human Bronchial Epithelial Cells
por: Arthur, Greer K., et al.
Publicado: (2015)

Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors
por: Melick, Chase H., et al.
Publicado: (2020)

Airway smooth muscle proliferation and survival is not modulated by mast cells
por: Kaur, D, et al.
Publicado: (2010)

TRIM31 promotes acute myeloid leukemia progression and sensitivity to daunorubicin through the Wnt/β-catenin signaling
por: Xiao, Yi, et al.
Publicado: (2020)

Aggressive migration in acidic pH of a glioblastoma cancer stem cell line in vitro is independent of ASIC and K(Ca)3.1 ion channels, but involves phosphoinositide 3-kinase
por: Cortés Franco, Klaus-Daniel, et al.
Publicado: (2022)

Prostaglandin E(2) Prevents Hyperosmolar-Induced Human Mast Cell Activation through Prostanoid Receptors EP(2) and EP(4)
por: Torres-Atencio, Ivonne, et al.
Publicado: (2014)

Human lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by K(Ca)3.1 K(+) channels
por: Roach, Katy M, et al.
Publicado: (2015)

K(Ca)3.1 Channel-Blockade Attenuates Airway Pathophysiology in a Sheep Model of Chronic Asthma
por: Van Der Velden, Joanne, et al.
Publicado: (2013)

Endoplasmic reticulum Ca(2+) release causes Rieske iron–sulfur protein-mediated mitochondrial ROS generation in pulmonary artery smooth muscle cells
por: Dong, Dapeng, et al.
Publicado: (2019)

Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation
por: Philipose, Sonia, et al.
Publicado: (2012)

Laropiprant attenuates EP(3) and TP prostanoid receptor-mediated thrombus formation
por: Philipose, Sonia, et al.
Publicado: (2012)

Co-Stimulation of Purinergic P2X4 and Prostanoid EP3 Receptors Triggers Synergistic Degranulation in Murine Mast Cells
por: Yoshida, Kazuki, et al.
Publicado: (2019)

The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca(2+)-activated large-conductance K(+) channels in endothelial cells
por: Bondarenko, Alexander I., et al.
Publicado: (2010)

Ablation of PI3K p110-α Prevents High-Fat Diet–Induced Liver Steatosis
por: Chattopadhyay, Mohar, et al.
Publicado: (2011)

Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T‐cell migration across the blood–brain barrier under flow in vitro
por: Rudolph, Henriette, et al.
Publicado: (2016)

Aire controls the recirculation of murine Foxp3(+) regulatory T‐cells back to the thymus
por: Cowan, Jennifer E., et al.
Publicado: (2018)

Tissue‐resident MAIT cell populations in human oral mucosa exhibit an activated profile and produce IL‐17
por: Sobkowiak, Michał J., et al.
Publicado: (2018)

Dynamic changes in intrathymic ILC populations during murine neonatal development
por: Jones, Rhys, et al.
Publicado: (2018)

Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells
por: Karrich, Julien J., et al.
Publicado: (2018)

Comprehensive characterization of myeloid cells during wound healing in healthy and healing‐impaired diabetic mice
por: Joshi, Natasha, et al.
Publicado: (2020)

A novel method to identify Post‐Aire stages of medullary thymic epithelial cell differentiation
por: Ferreirinha, Pedro, et al.
Publicado: (2020)

Analysis of lung stromal expression of the atypical chemokine receptor ACKR2 reveals unanticipated expression in murine blood endothelial cells
por: Hansell, Christopher A.H., et al.
Publicado: (2020)

CD169(+) subcapsular sinus macrophage‐derived microvesicles are associated with light zone follicular dendritic cells
por: Chen, Xin, et al.
Publicado: (2022)

Targeted delivery of a vaccine protein to Langerhans cells in the human skin via the C‐type lectin receptor Langerin
por: Bellmann, Lydia, et al.
Publicado: (2022)

EP4-mediated prostanoid signalling promotes oral cancer progression
por: Sapienza, Karen, et al.
Publicado: (2010)

E-type prostanoid receptor 4 (EP4) in disease and therapy
por: Konya, Viktoria, et al.
Publicado: (2013)

Improved homology modeling of the human & rat EP(4) prostanoid receptors
por: Holt, Melissa C., et al.
Publicado: (2019)

Increased constitutive αSMA and Smad2/3 expression in idiopathic pulmonary fibrosis myofibroblasts is K(Ca)3.1-dependent
por: Roach, Katy M, et al.
Publicado: (2014)

Ca(2+) Signals Generated by CatSper and Ca(2+) Stores Regulate Different Behaviors in Human Sperm
por: Alasmari, Wardah, et al.
Publicado: (2013)

Lobe-specific Functions of Ca(2+)·Calmodulin in αCa(2+)·Calmodulin-dependent Protein Kinase II Activation
por: Jama, Abdirahman M., et al.
Publicado: (2011)

Hydrophobic Motif Phosphorylation Is Not Required for Activation Loop Phosphorylation of p70 Ribosomal Protein S6 Kinase 1 (S6K1)
por: Keshwani, Malik M., et al.
Publicado: (2011)

Scutellarin attenuates hypoxia/reoxygenation injury in hepatocytes by inhibiting apoptosis and oxidative stress through regulating Keap1/Nrf2/ARE signaling
por: Wu, Haiyuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qp4b1ssvlhh2c7hj3k5jocrrk0