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Association of Polymorphisms of the CHI3L1 Gene with Asthma and Atopy: A Populations-Based Study of 6514 Danish Adults

BACKGROUND: YKL-40 is a chitinase-like glycoprotein encoded by the chitinase 3-like 1 gene, CHI3L1, localized at chromosome 1q32.1. Increased levels of serum YKL-40 have been reported to be a biomarker for asthma and a reduced lung function. Interestingly, the C-allele of the -131 C→G (rs4950928) po...

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Detalles Bibliográficos
Autores principales: Rathcke, Camilla Noelle, Holmkvist, Johan, Husmoen, Lise Lotte N., Hansen, Torben, Pedersen, Oluf, Vestergaard, Henrik, Linneberg, Allan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699472/
https://www.ncbi.nlm.nih.gov/pubmed/19568425
http://dx.doi.org/10.1371/journal.pone.0006106