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Cleavage of a model DNA replication fork by a Type I restriction endonuclease

Cleavage of a DNA replication fork leads to fork restoration by recombination repair. In prokaryote cells carrying restriction–modification systems, fork passage reduces genome methylation by the modification enzyme and exposes the chromosome to attack by the restriction enzyme. Various observations...

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Detalles Bibliográficos
Autores principales: Ishikawa, Ken, Handa, Naofumi, Kobayashi, Ichizo
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699502/
https://www.ncbi.nlm.nih.gov/pubmed/19357093
http://dx.doi.org/10.1093/nar/gkp214