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Nucleotide analogs and molecular modeling studies reveal key interactions involved in substrate recognition by the yeast RNA triphosphatase
RNA triphosphatases (RTPases) are involved in the addition of the distinctive cap structure found at the 5′ ends of eukaryotic mRNAs. Fungi, protozoa and some DNA viruses possess an RTPase that belongs to the triphosphate tunnel metalloenzyme family of enzymes that can also hydrolyze nucleoside trip...
Autores principales: | Issur, Moheshwarnath, Despins, Simon, Bougie, Isabelle, Bisaillon, Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699512/ https://www.ncbi.nlm.nih.gov/pubmed/19372271 http://dx.doi.org/10.1093/nar/gkp227 |
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