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Local and global effects of strong DNA bending induced during molecular dynamics simulations

DNA bending plays an important role in many biological processes, but its molecular and energetic details as a function of base sequence remain to be fully understood. Using a recently developed restraint, we have studied the controlled bending of four different B-DNA oligomers using molecular dynam...

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Detalles Bibliográficos
Autores principales:	Curuksu, Jeremy, Zacharias, Martin, Lavery, Richard, Zakrzewska, Krystyna
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699519/ https://www.ncbi.nlm.nih.gov/pubmed/19380377 http://dx.doi.org/10.1093/nar/gkp234

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