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Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications
Post-translational modifications (PTMs) of histones play a role in modifying chromatin structure for DNA-templated processes in the eukaryotic nucleus, such as transcription, replication, recombination and repair; thus, histone PTMs are considered major players in the epigenetic control of these pro...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699528/ https://www.ncbi.nlm.nih.gov/pubmed/19443446 http://dx.doi.org/10.1093/nar/gkp273 |