Cargando…

Free Fatty Acids Link Metabolism and Regulation of the Insulin-Sensitizing Fibroblast Growth Factor-21

OBJECTIVE: Fibroblast growth factor (FGF)-21 improves insulin sensitivity and lipid metabolism in obese or diabetic animal models, while human studies revealed increased FGF-21 levels in obesity and type 2 diabetes. Given that FGF-21 has been suggested to be a peroxisome proliferator–activator recep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mai, Knut, Andres, Janin, Biedasek, Katrin, Weicht, Jessica, Bobbert, Thomas, Sabath, Markus, Meinus, Sabine, Reinecke, Franziska, Möhlig, Matthias, Weickert, Martin O., Clemenz, Markus, Pfeiffer, Andreas F.H., Kintscher, Ulrich, Spuler, Simone, Spranger, Joachim
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699854/ https://www.ncbi.nlm.nih.gov/pubmed/19401423 http://dx.doi.org/10.2337/db08-1775

Ejemplares similares

Fibroblast Growth Factor 21 Predicts the Metabolic Syndrome and Type 2 Diabetes in Caucasians
por: Bobbert, Thomas, et al.
Publicado: (2013)

Skeletal Muscle 11beta-HSD1 Controls Glucocorticoid-Induced Proteolysis and Expression of E3 Ubiquitin Ligases Atrogin-1 and MuRF-1
por: Biedasek, Katrin, et al.
Publicado: (2011)

Glucose-Dependent Insulinotropic Polypeptide Reduces Fat-Specific Expression and Activity of 11β-Hydroxysteroid Dehydrogenase Type 1 and Inhibits Release of Free Fatty Acids
por: Gögebakan, Özlem, et al.
Publicado: (2012)

Hepatic Insulin Clearance Is Closely Related to Metabolic Syndrome Components
por: Pivovarova, Olga, et al.
Publicado: (2013)

Renal function is independently associated with circulating betatrophin
por: Maurer, Lukas, et al.
Publicado: (2017)

A1C Is Associated With Intima-Media Thickness in Individuals With Normal Glucose Tolerance
por: Bobbert, Thomas, et al.
Publicado: (2010)

A distinct metabolic signature predicts development of fasting plasma glucose
por: Hische, Manuela, et al.
Publicado: (2012)

Histone Deacetylase 6 (HDAC6) Is an Essential Modifier of Glucocorticoid-Induced Hepatic Gluconeogenesis
por: Winkler, Robin, et al.
Publicado: (2012)

Changes in dominant groups of the gut microbiota do not explain cereal-fiber induced improvement of whole-body insulin sensitivity
por: Weickert, Martin O, et al.
Publicado: (2011)

PPARgamma activation attenuates T-lymphocyte-dependent inflammation of adipose tissue and development of insulin resistance in obese mice
por: Foryst-Ludwig, Anna, et al.
Publicado: (2010)

Attachment style contributes to the outcome of a multimodal lifestyle intervention
por: Kiesewetter, Sybille, et al.
Publicado: (2012)

Liver Fat Scores for Noninvasive Diagnosis and Monitoring of Nonalcoholic Fatty Liver Disease in Epidemiological and Clinical Studies
por: Reinshagen, Mona, et al.
Publicado: (2023)

Lack of Association between the Tagging SNP A+930→G of SOCS3 and Type 2 Diabetes Mellitus: Meta-Analysis of Four Independent Study Populations
por: Fischer-Rosinsky, Antje, et al.
Publicado: (2008)

Affordability of Different Isocaloric Healthy Diets in Germany—An Assessment of Food Prices for Seven Distinct Food Patterns
por: Kabisch, Stefan, et al.
Publicado: (2021)

Metabolic Actions of Estrogen Receptor Beta (ERβ) are Mediated by a Negative Cross-Talk with PPARγ
por: Foryst-Ludwig, Anna, et al.
Publicado: (2008)

Metabolic impact of weight loss induced reduction of adipose ACE-2 – Potential implication in COVID-19 infections?
por: Li, Linna, et al.
Publicado: (2020)

Weight loss-induced improvement of body weight and insulin sensitivity is not amplified by a subsequent 12-month weight maintenance intervention but is predicted by adaption of adipose atrial natriuretic peptide system: 48-month results of a randomized controlled trial
por: Li, Linna, et al.
Publicado: (2022)

Hepatic Energy Metabolism under the Local Control of the Thyroid Hormone System
por: Seifert, Joshua, et al.
Publicado: (2023)

Psychodynamic mechanism and weight reduction in obesity group therapy – first observations with different attachment styles
por: Kiesewetter, Sybille, et al.
Publicado: (2010)

Long-term effects of a food pattern on cardiovascular risk factors and age-related changes of muscular and cognitive function
por: Wernicke, Charlotte, et al.
Publicado: (2020)

Long-term impact of the metabolic status on weight loss-induced health benefits
por: Soll, Dominik, et al.
Publicado: (2022)

High‐Saturated‐Fat Diet Increases Circulating Angiotensin‐Converting Enzyme, Which Is Enhanced by the rs4343 Polymorphism Defining Persons at Risk of Nutrient‐Dependent Increases of Blood Pressure
por: Schüler, Rita, et al.
Publicado: (2017)

Fibroblast Growth Factor 21 Mediates Specific Glucagon Actions
por: Habegger, Kirk M., et al.
Publicado: (2013)

Prolonged treatment with vitamin D in postmenopausal women with primary hyperparathyroidism
por: Rao, Ranganathan R, et al.
Publicado: (2012)

5-Aminovaleric acid betaine predicts impaired glucose metabolism and diabetes
por: Haberbosch, Linus, et al.
Publicado: (2023)

Dietary Fat Intake Modulates Effects of a Frequent ACE Gene Variant on Glucose Tolerance with association to Type 2 Diabetes
por: Schüler, Rita, et al.
Publicado: (2017)

Clinical outcome of a patient with lysosomal acid lipase deficiency and first results after initiation of treatment with Sebelipase alfa: A case report
por: Soll, Dominik, et al.
Publicado: (2019)

Interaction of circulating GLP-1 and the response of the dorsolateral prefrontal cortex to food-cues predicts body weight development
por: Maurer, Lukas, et al.
Publicado: (2019)

Evidence That Kidney Function but Not Type 2 Diabetes Determines Retinol-Binding Protein 4 Serum Levels
por: Henze, Andrea, et al.
Publicado: (2008)

Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana
por: Redestig, Henning, et al.
Publicado: (2007)

Fetuin-B, a potential link of liver-adipose tissue cross talk during diet-induced weight loss–weight maintenance
por: Li, Linna, et al.
Publicado: (2021)

Quantifying the Improvement of Surrogate Indices of Hepatic Insulin Resistance Using Complex Measurement Techniques
por: Hattersley, John G., et al.
Publicado: (2012)

Navigating the Impacts of Dementia: The Experience of Male Spousal Carers
por: Tolhurst, Edward, et al.
Publicado: (2023)

The Spousal Unit and Dementia: Investigating the Relational Basis of the Couplehood Concept
por: Weicht, Bernhard, et al.
Publicado: (2023)

Sexual Dimorphic Regulation of Body Weight Dynamics and Adipose Tissue Lipolysis
por: Benz, Verena, et al.
Publicado: (2012)

Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study
por: Weber-Carstens, Steffen, et al.
Publicado: (2010)

Association of fibroblast growth factor 21 with alcohol consumption and alcohol liver cirrhosis
por: Wagner-Skacel, Jolana, et al.
Publicado: (2020)

A Polymorphism Within the Connective Tissue Growth Factor (CTGF) Gene has No Effect on Non-Invasive Markers of Beta-Cell Area and Risk of Type 2 Diabetes
por: Pivovarova, Olga, et al.
Publicado: (2011)

Food Authentication: Identification and Quantitation of Different Tuber Species via Capillary Gel Electrophoresis and Real-Time PCR
por: Schelm, Stefanie, et al.
Publicado: (2020)

Consequences of aneuploidy in human fibroblasts with trisomy 21
por: Hwang, Sunyoung, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dltvhf9t77vie9g49l8vrk2adk