(Pro)renin Receptor–Mediated Signal Transduction and Tissue Renin-Angiotensin System Contribute to Diabetes-Induced Retinal Inflammation

OBJECTIVE: The term “receptor-associated prorenin system” (RAPS) refers to the pathogenic mechanisms whereby prorenin binding to its receptor dually activates the tissue renin-angiotensin system (RAS) and RAS-independent intracellular signaling via the receptor. The aim of the present study was to d...

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Detalles Bibliográficos
Autores principales: Satofuka, Shingo, Ichihara, Atsuhiro, Nagai, Norihiro, Noda, Kousuke, Ozawa, Yoko, Fukamizu, Akiyoshi, Tsubota, Kazuo, Itoh, Hiroshi, Oike, Yuichi, Ishida, Susumu
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699867/
https://www.ncbi.nlm.nih.gov/pubmed/19389828
http://dx.doi.org/10.2337/db08-0254

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