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Association of Type 2 Diabetes Candidate Polymorphisms in KCNQ1 With Incretin and Insulin Secretion

OBJECTIVE: KCNQ1 gene polymorphisms are associated with type 2 diabetes. This linkage appears to be mediated by altered β-cell function. In an attempt to study underlying mechanisms, we examined the effect of four KCNQ1 single nucleotide polymorphisms (SNPs) on insulin secretion upon different stimu...

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Detalles Bibliográficos
Autores principales:	Müssig, Karsten, Staiger, Harald, Machicao, Fausto, Kirchhoff, Kerstin, Guthoff, Martina, Schäfer, Silke A., Kantartzis, Konstantinos, Silbernagel, Günther, Stefan, Norbert, Holst, Jens J., Gallwitz, Baptist, Häring, Hans-Ulrich, Fritsche, Andreas
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699873/ https://www.ncbi.nlm.nih.gov/pubmed/19366866 http://dx.doi.org/10.2337/db08-1589

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