Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Expression

OBJECTIVE: The peroxisome proliferator–activated receptor-γ coactivator (PGC)-1 family of transcriptional coactivators controls hepatic function by modulating the expression of key metabolic enzymes. Hepatic gain of function and complete genetic ablation of PGC-1α show that this coactivator is impor...

Descripción completa

Detalles Bibliográficos
Autores principales: Estall, Jennifer L., Kahn, Mario, Cooper, Marcus P., Fisher, ffolliott Martin, Wu, Michele K., Laznik, Dina, Qu, Lishu, Cohen, David E., Shulman, Gerald I., Spiegelman, Bruce M.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699879/
https://www.ncbi.nlm.nih.gov/pubmed/19366863
http://dx.doi.org/10.2337/db08-1571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699879/
https://www.ncbi.nlm.nih.gov/pubmed/19366863
http://dx.doi.org/10.2337/db08-1571

Ejemplares similares