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Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α Expression

OBJECTIVE: The peroxisome proliferator–activated receptor-γ coactivator (PGC)-1 family of transcriptional coactivators controls hepatic function by modulating the expression of key metabolic enzymes. Hepatic gain of function and complete genetic ablation of PGC-1α show that this coactivator is impor...

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Detalles Bibliográficos
Autores principales:	Estall, Jennifer L., Kahn, Mario, Cooper, Marcus P., Fisher, ffolliott Martin, Wu, Michele K., Laznik, Dina, Qu, Lishu, Cohen, David E., Shulman, Gerald I., Spiegelman, Bruce M.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699879/ https://www.ncbi.nlm.nih.gov/pubmed/19366863 http://dx.doi.org/10.2337/db08-1571

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