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Aqueous humor and serum penetration of tacrolimus after topical and oral administration in rats: an absorption study
PURPOSE: To investigate the penetration of tacrolimus to the aqueous and serum after topical and oral administration. METHODS: Thirty Wistar rats were divided into three groups. In the first group (n = 12), a single dose of 0.3 % isotonic tacrolimus solution was applied topically to the rat eyes. Th...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699987/ https://www.ncbi.nlm.nih.gov/pubmed/19668467 |