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Enhanced cerebrovascular expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 via the MEK/ERK pathway during cerebral ischemia in the rat

BACKGROUND: Cerebral ischemia is usually characterized by a reduction in local blood flow and metabolism and by disruption of the blood-brain barrier in the infarct region. The formation of oedema and opening of the blood-brain barrier in stroke is associated with enhanced expression of metalloprote...

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Detalles Bibliográficos
Autores principales:	Maddahi, Aida, Chen, Qingwen, Edvinsson, Lars
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700114/ https://www.ncbi.nlm.nih.gov/pubmed/19497125 http://dx.doi.org/10.1186/1471-2202-10-56

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