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Pten Dose Dictates Cancer Progression in the Prostate

Complete inactivation of the PTEN tumor suppressor gene is extremely common in advanced cancer, including prostate cancer (CaP). However, one PTEN allele is already lost in the vast majority of CaPs at presentation. To determine the consequence of PTEN dose variations on cancer progression, we have...

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Detalles Bibliográficos
Autores principales:	Trotman, Lloyd C, Niki, Masaru, Dotan, Zohar A, Koutcher, Jason A, Di Cristofano, Antonio, Xiao, Andrew, Khoo, Alan S, Roy-Burman, Pradip, Greenberg, Norman M, Dyke, Terry Van, Cordon-Cardo, Carlos, Pandolfi, Pier Paolo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2003
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270016/ https://www.ncbi.nlm.nih.gov/pubmed/14691534 http://dx.doi.org/10.1371/journal.pbio.0000059

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