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GAD2 on Chromosome 10p12 Is a Candidate Gene for Human Obesity
The gene GAD2 encoding the glutamic acid decarboxylase enzyme (GAD65) is a positional candidate gene for obesity on Chromosome 10p11–12, a susceptibility locus for morbid obesity in four independent ethnic populations. GAD65 catalyzes the formation of γ-aminobutyric acid (GABA), which interacts with...
Autores principales: | Boutin, Philippe, Dina, Christian, Vasseur, Francis, Dubois, Séverine, Corset, Laetitia, Séron, Karin, Bekris, Lynn, Cabellon, Janice, Neve, Bernadette, Vasseur-Delannoy, Valérie, Chikri, Mohamed, Charles, M. Aline, Clement, Karine, Lernmark, Ake, Froguel, Philippe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC270019/ https://www.ncbi.nlm.nih.gov/pubmed/14691540 http://dx.doi.org/10.1371/journal.pbio.0000068 |
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