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A c-Myc–SIRT1 feedback loop regulates cell growth and transformation

The protein deacetylase SIRT1 has been implicated in a variety of cellular functions, including development, cellular stress responses, and metabolism. Increasing evidence suggests that similar to its counterpart, Sir2, in yeast, Caenorhabditis elegans, and Drosophila melanogaster, SIRT1 may functio...

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Detalles Bibliográficos
Autores principales: Yuan, Jian, Minter-Dykhouse, Katherine, Lou, Zhenkun
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700370/
https://www.ncbi.nlm.nih.gov/pubmed/19364925
http://dx.doi.org/10.1083/jcb.200809167

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