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The decision to enter mitosis: feedback and redundancy in the mitotic entry network

The decision to enter mitosis is mediated by a network of proteins that regulate activation of the cyclin B–Cdk1 complex. Within this network, several positive feedback loops can amplify cyclin B–Cdk1 activation to ensure complete commitment to a mitotic state once the decision to enter mitosis has...

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Detalles Bibliográficos
Autores principales: Lindqvist, Arne, Rodríguez-Bravo, Verónica, Medema, René H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700378/
https://www.ncbi.nlm.nih.gov/pubmed/19364923
http://dx.doi.org/10.1083/jcb.200812045

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