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Erk1/2 MAP kinases are required for epidermal G2/M progression
Erk1/2 mitogen-activated protein kinases (MAPKs) are often hyperactivated in human cancers, where they affect multiple processes, including proliferation. However, the effects of Erk1/2 loss in normal epithelial tissue, the setting of most extracellular signal-regulated kinase (Erk)–associated neopl...
Autores principales: | Dumesic, Phillip A., Scholl, Florence A., Barragan, Deborah I., Khavari, Paul A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700391/ https://www.ncbi.nlm.nih.gov/pubmed/19414607 http://dx.doi.org/10.1083/jcb.200804038 |
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